FHOD1 and NLGN3

Data Source:
BioGRID (two hybrid)

		FHOD1	NLGN3
Description		formin homology 2 domain containing 1	neuroligin 3
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Intercalated Disc Membrane Bleb	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endocytic Vesicle Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Actin Filament Binding	Protein Binding Signaling Receptor Activity Neurexin Family Protein Binding Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Nuclear Migration Cortical Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Actin Filament Network Formation Establishment Of Centrosome Localization	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Receptor-mediated Endocytosis Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Learning Adult Behavior Social Behavior Synaptic Vesicle Endocytosis Axon Extension Modulation Of Chemical Synaptic Transmission Synapse Organization Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Rhythmic Synaptic Transmission Inhibitory Postsynaptic Potential Vocalization Behavior Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of AMPA Receptor Activity
Pathways			Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Prostate cancer ( 25217961)
Interacting Genes		22 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 TRIM21 YWHAZ ZMYND8	55 interacting genes: ALPP AP2A2 ATF4 C1orf122 C1QA CCAR2 CGB3 CTSD DLG2 DLG3 DLG4 DPEP2 EBPL EFS FANCG FBLN1 FHOD1 FKBP1A FLNA GDF15 GUK1 HID1 ITPRIP LGALS1 MAN2C1 MAP1S MEOX2 MIEN1 NFATC4 NRDC NRXN1 NRXN2 NRXN3 OAZ1 OR1F12 PKIB PLB1 PLCB4 PRDX2 PSAP PSG1 PSG11 PSG3 PSG4 PSG5 QARS1 SPAG5 SPINT1 SSR4 TNNT3 TRIM33 TXNIP UBQLN1 UBXN6 UQCRC1
Entrez ID		29109	54413
HPRD ID		06049	02275
Ensembl ID		ENSG00000135723	ENSG00000196338
Uniprot IDs		A0A068F7M9 Q9Y613	B7Z3P8 Q4G160 Q6MZK0 Q9NZ94 X5D2P6 X5D7L6 X5DNV3
PDB IDs		3DAD
Enriched GO Terms of Interacting Partners?
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