FAM156A and ATRIP

Data Source:
BioGRID (two hybrid)

		FAM156A	ATRIP
Description		family with sequence similarity 156 member A	ATR interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Integral Component Of Membrane	Nucleoplasm
	Molecular Function	Protein Binding Methylated Histone Binding	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process		DNA Damage Checkpoint DNA Replication DNA Repair Interstrand Cross-link Repair Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		7 interacting genes: ATRIP CRACR2A GADD45G MAGEA11 SAT1 TEX11 TFIP11	22 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2 ZBTB14
Entrez ID		29057	84126
HPRD ID		06683
Ensembl ID		ENSG00000268350	ENSG00000164053
Uniprot IDs		Q8NDB6	A0A024R2U4 A0A024R307 Q8WXE1
PDB IDs			4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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