IFT81 and SLC8B1

Data Source:
BioGRID (proximity labelling technology)

		IFT81	SLC8B1
Description		intraflagellar transport 81	solute carrier family 8 member B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip	Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Crista Integral Component Of Mitochondrial Membrane
	Molecular Function	Protein Binding Tubulin Binding	Calcium:sodium Antiporter Activity Cation Transmembrane Transporter Activity Calcium:cation Antiporter Activity Protein Homodimerization Activity Calcium:sodium Antiporter Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential
	Biological Process	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly	Ion Transport Cation Transport Mitochondrial Calcium Ion Transmembrane Transport Cellular Calcium Ion Homeostasis Sodium Ion Transmembrane Transport Glucose Homeostasis Regulation Of Insulin Secretion Response To Stimulus Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Calcium Ion Homeostasis Regulation Of Cardiac Muscle Cell Membrane Potential Calcium Export From The Mitochondrion Regulation Of Lymphocyte Chemotaxis Regulation Of Store-operated Calcium Entry
Pathways		Intraflagellar transport Intraflagellar transport	Sodium/Calcium exchangers Mitochondrial calcium ion transport
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)
Interacting Genes		2 interacting genes: APP IFT74
Entrez ID		28981	80024
HPRD ID		09266	15354
Ensembl ID		ENSG00000122970	ENSG00000089060
Uniprot IDs		A0A024RBJ1 Q8WYA0	Q6J4K2
PDB IDs
Enriched GO Terms of Interacting Partners?
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