IFT81 and RPH3A

Data Source:
BioGRID (affinity chromatography technology)

		IFT81	RPH3A
Description		intraflagellar transport 81	rabphilin 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip	Golgi Apparatus Cytosol Synaptic Vesicle Extrinsic Component Of Membrane Secretory Granule Synaptic Vesicle Membrane Protein-containing Complex Neuron Projection Dendritic Spine Synapse Postsynaptic Membrane
	Molecular Function	Protein Binding Tubulin Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Selenium Binding Phosphate Ion Binding Protein-containing Complex Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly	Intracellular Protein Transport Spontaneous Neurotransmitter Secretion
Pathways		Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)	Alcohol consumption (max-drinks) ( 29460428) Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Chloride levels ( 29403010) Coronary artery disease ( 32469254) LDL cholesterol levels ( 32203549) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Low density lipoprotein cholesterol levels ( 32154731 29403010) Low HDL-cholesterol levels ( 31006500) Platelet count ( 22139419) Serum uric acid levels ( 32514006) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: APP IFT74	12 interacting genes: ADD2 CASK GCH1 MYO5A NRXN1 RAB15 RAB27A RAB27B RAB3A RAB3B RAB8A YWHAH
Entrez ID		28981	22895
HPRD ID		09266	15273
Ensembl ID		ENSG00000122970	ENSG00000089169
Uniprot IDs		A0A024RBJ1 Q8WYA0	A0A024RBK6 Q9Y2J0
PDB IDs
Enriched GO Terms of Interacting Partners?
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