IFT81 and SDS

Data Source:
BioGRID (biochemical)

		IFT81	SDS
Description		intraflagellar transport 81	serine dehydratase
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip	Mitochondrion Cytosol
	Molecular Function	Protein Binding Tubulin Binding	L-serine Ammonia-lyase Activity L-threonine Ammonia-lyase Activity Protein Binding Pyridoxal Phosphate Binding Protein Homodimerization Activity
	Biological Process	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly	Gluconeogenesis L-serine Catabolic Process Threonine Catabolic Process Isoleucine Biosynthetic Process L-threonine Catabolic Process To Glycine Pyruvate Biosynthetic Process
Pathways		Intraflagellar transport Intraflagellar transport	Threonine catabolism
Drugs			Pyridoxal phosphate Serine
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)	Body mass index ( 26426971) Low high density lipoprotein cholesterol levels ( 26879886)
Interacting Genes		2 interacting genes: APP IFT74	3 interacting genes: DDI1 HGS TGM7
Entrez ID		28981	10993
HPRD ID		09266	01633
Ensembl ID		ENSG00000122970	ENSG00000135094
Uniprot IDs		A0A024RBJ1 Q8WYA0	P20132 Q8WW81
PDB IDs			1P5J 4H27
Enriched GO Terms of Interacting Partners?
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