IFT81 and ERP29

Data Source:
BioGRID (proximity labelling technology)

		IFT81	ERP29
Description		intraflagellar transport 81	endoplasmic reticulum protein 29
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Cell Surface Membrane Transport Vesicle Melanosome
	Molecular Function	Protein Binding Tubulin Binding	Protein Disulfide Isomerase Activity Protein Binding Protein Homodimerization Activity Chaperone Binding
	Biological Process	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly	Activation Of MAPK Activity Positive Regulation Of Protein Phosphorylation Protein Folding Intracellular Protein Transport Protein Secretion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Protein Phosphopantetheinylation Protein Unfolding Negative Regulation Of Protein Secretion Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)	Body mass index ( 26426971) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		2 interacting genes: APP IFT74	18 interacting genes: ADIPOQ BMP10 C3orf52 DESI1 GLP1R HMG20B HSPA5 NRM SGTA SGTB SLC35B4 SLC38A7 TMBIM6 TMEM86B TSPO2 UBQLN1 UBQLN2 UBQLN4
Entrez ID		28981	10961
HPRD ID		09266	03794
Ensembl ID		ENSG00000122970	ENSG00000089248
Uniprot IDs		A0A024RBJ1 Q8WYA0	F8VY02 P30040 V9HW71
PDB IDs			2QC7 5V8Z 5V90
Enriched GO Terms of Interacting Partners?
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