ACAD9 and HMCES

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		ACAD9	HMCES
Description		acyl-CoA dehydrogenase family member 9	5-hydroxymethylcytosine binding, ES cell specific
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Dendrite Mitochondrial Membrane	Replication Fork
	Molecular Function	Fatty-acyl-CoA Binding Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity	Single-stranded DNA Binding DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Protein Binding Peptidase Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Mitochondrial Respiratory Chain Complex I Assembly Medium-chain Fatty Acid Metabolic Process	Proteolysis Cellular Response To DNA Damage Stimulus Protein-DNA Covalent Cross-linking Positive Regulation Of Isotype Switching Double-strand Break Repair Via Alternative Nonhomologous End Joining
Pathways		Complex I biogenesis
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Dental caries ( 23064961) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)
Interacting Genes			3 interacting genes: APP FBXO25 NEDD4
Entrez ID		28976	56941
HPRD ID		12412	13119
Ensembl ID		ENSG00000177646	ENSG00000183624
Uniprot IDs		Q9H845	Q96FZ2
PDB IDs			5KO9 6OE7 6OEA 6OEB 6OOV
Enriched GO Terms of Interacting Partners?
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