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FFAR2 and ALOX5AP
Data Source:
BioGRID
(two hybrid)
FFAR2
ALOX5AP
Description
free fatty acid receptor 2
arachidonate 5-lipoxygenase activating protein
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Projection
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Nuclear Membrane
Molecular Function
G Protein-coupled Receptor Activity
Protein Binding
Lipid Binding
Glutathione Transferase Activity
Leukotriene-C4 Synthase Activity
Glutathione Peroxidase Activity
Protein Binding
Enzyme Activator Activity
Protein N-terminus Binding
Arachidonic Acid Binding
Biological Process
Leukocyte Chemotaxis Involved In Inflammatory Response
Mucosal Immune Response
Regulation Of Acute Inflammatory Response
Positive Regulation Of Cytokine Production Involved In Immune Response
Cell Surface Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus
G Protein-coupled Receptor Signaling Pathway
Lipid Storage
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-8 Production
Glucose Homeostasis
Fat Cell Differentiation
Cellular Response To Fatty Acid
Regulation Of Peptide Hormone Secretion
Leukotriene Metabolic Process
Leukotriene Biosynthetic Process
Lipoxygenase Pathway
Regulation Of Catalytic Activity
Protein Homotrimerization
Cellular Response To Calcium Ion
Cellular Oxidant Detoxification
Lipoxin Biosynthetic Process
Pathways
G alpha (q) signalling events
Free fatty acid receptors
Synthesis of 5-eicosatetraenoic acids
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Lipoxins (LX)
Drugs
DG031
AM103
Fiboflapon
Diseases
GWAS
Hemoglobin (
32888494
)
Metabolite levels (
23823483
)
Monocyte percentage of white cells (
32888494
)
Neutrophil count (
32888494
)
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) (
24025145
)
General risk tolerance (MTAG) (
30643258
)
Non-word repetition (
23738518
)
Interacting Genes
110 interacting genes:
AGPAT4
AGTRAP
ALOX5AP
APOD
ATP13A1
ATP6V0C
BMP10
BNIP3
BTN2A2
C11orf24
C3orf52
C4orf3
CACNG1
CBLIF
CCDC167
CD82
CDIPT
CFHR5
CGRRF1
CLDN4
CLDND2
CLEC1A
CMTM5
CMTM7
CNIH1
COL4A5
CXCL16
CXCL9
CYB561A3
CYB5R2
DERL1
EDDM3B
EMP1
ERG28
FAM20B
FAM3C
FAXDC2
FCER1G
FIS1
FXYD3
FXYD6
FZD7
GALNT15
GJB2
GNAO1
GNAQ
GPR37L1
GUCA2A
GYPA
IFITM3
IGF1R
KRT1
KTN1
LAPTM4A
LAT
LEPROTL1
LHFPL5
LPAR3
MALL
MFSD5
MS4A13
NAT8
NIPAL4
NKG7
NRM
NSG1
NUCB2
OR10AG1
PEX16
PLP1
PMP22
PNLIPRP1
RPRM
RTP2
RUSF1
SACM1L
SCGB1D1
SELENOK
SLC30A2
SLC35B4
SLC35C2
SLC35E3
SLC38A1
SLC39A9
SLC41A1
SMAGP
SMCO4
SMIM1
STRIT1
STX8
SYNDIG1
TEX264
TM4SF4
TMEM11
TMEM120B
TMEM144
TMEM147
TMEM203
TMEM239
TMEM262
TMEM60
TMEM86A
TMEM97
TNF
TSPO2
UNC50
UPK1B
YIF1A
YIPF2
YIPF6
10 interacting genes:
ALOX5
AQP6
CLIC1
FFAR2
GPR42
LTC4S
NAPB
OPRM1
SLC29A2
TMEM120B
Entrez ID
2867
241
HPRD ID
04824
04742
Ensembl ID
ENSG00000126262
ENSG00000132965
Uniprot IDs
C6KYL4
O15552
A0A087WW23
P20292
PDB IDs
2Q7M
2Q7R
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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