YIPF6 and GJB1

Data Source:
BioGRID (two hybrid)

		YIPF6	GJB1
Description		Yip1 domain family member 6	gap junction protein beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Golgi Medial Cisterna Cis-Golgi Network Trans-Golgi Network Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	Intestinal Epithelial Cell Development	Cell-cell Signaling Nervous System Development Gap Junction Assembly Transmembrane Transport
Pathways		Golgi Associated Vesicle Biogenesis	Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Male-pattern baldness ( 28196072)
Interacting Genes		89 interacting genes: APOL2 AQP2 AQP6 ARL13B ATP6V0E1 CD79A CGRRF1 CISD2 CLN8 CNR2 CPLX4 CRB3 CREB3L1 CREB3L3 CXorf66 CYSLTR2 EBP EFNA5 ELOVL4 ERGIC3 F2RL1 FAM209A FCER1G FFAR2 FKBP7 GJA5 GJA8 GJB1 GPR101 GPR152 GPR42 GPX8 HSD17B11 IL10RA IL1RL1 IL27RA JKAMP KCNJ6 KCNK5 LMNA LRRC25 LRRC3B LRRC4C LY6G6C LYVE1 MFSD14B MFSD5 MMD MS4A3 MTIF3 NDUFAF1 ODF4 PDZK1IP1 PSCA RAET1L RETREG3 RHCG RNF185 SLC10A1 SLC10A6 SLC12A7 SLC17A8 SLC18A1 SLC30A4 SLC30A8 SLC35C2 SLC38A7 SLC39A1 SLC39A2 SLC7A14 SLC7A8 SSMEM1 STOM TCTA THAP4 TMEM106C TMEM11 TMEM130 TMEM14B TMEM237 TMEM31 TMEM71 TMX2 TRARG1 TRHR TVP23B ULBP2 YIPF1 YIPF2	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		286451	2705
HPRD ID		06639	02367
Ensembl ID		ENSG00000181704	ENSG00000169562
Uniprot IDs		Q96EC8	A0A654ICJ7 P08034
PDB IDs			1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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