CCDC88B and DTNB

Data Source:
BioGRID (two hybrid)

		CCDC88B	DTNB
Description		coiled-coil domain containing 88B	dystrobrevin beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Membrane	Cytoplasm Plasma Membrane Synapse
	Molecular Function	Protein Binding Microtubule Binding Dynein Light Intermediate Chain Binding	Protein Binding Zinc Ion Binding
	Biological Process	Positive Regulation Of Cytokine Production Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Positive Regulation Of T Cell Proliferation Defense Response To Protozoan Positive Regulation Of T Cell Activation	Synaptic Signaling
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233) Keratinocyte cancer (MTAG) ( 31174203) Leprosy ( 25642632) Medication use (thyroid preparations) ( 31015401) Primary biliary cholangitis ( 26394269) Primary sclerosing cholangitis ( 27992413) Sarcoidosis ( 22837380) Triglyceride levels ( 32154731)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cutaneous malignant melanoma ( 32341527) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Height ( 18391951) Heschl's gyrus morphology ( 25130324) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) LDL cholesterol ( 21347282) Macular thickness ( 30535121) Multiple myeloma ( 22120009 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Nevus count or cutaneous melanoma ( 32341527) Resistant hypertension ( 31545351) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 28552196) Working memory ( 31598132)
Interacting Genes		40 interacting genes: BEX2 C1orf109 CARD9 CCHCR1 CDK18 CWF19L2 DEF6 DTNB EXOSC5 FAM161A FAM161B GEM HCK HOXB5 JAKMIP2 KANK2 LMNB1 LMNB2 LMO1 LNX1 NME7 PBX2 PIN1 PLEKHA5 PPP1R18 RALBP1 RBM7 RINT1 SH2D4A SH3KBP1 SRPK2 TBC1D22B TRAF3IP3 TSG101 TSGA10 TSGA10IP TSHZ2 TXLNB USP2 ZC2HC1C	62 interacting genes: ABI1 ABI2 ABI3 AMOTL2 BEGAIN CBY2 CCDC136 CCDC196 CCDC85B CCDC88B CCHCR1 CEP55 CEP63 COG6 CTBP2 DEUP1 DMD DTNBP1 FAM167A FSD2 GGA1 HMG20A INSYN1 KIF5A KIF5B KRT15 KRT27 KRT31 KRT33B KRT35 KRT38 KRT40 LURAP1 MB21D2 MTUS2 NDEL1 NUP62 PICK1 POU6F2 PPFIA1 PPFIBP2 PPP1R13B PRKAR1B PRTFDC1 SNTA1 SNTG1 SNTG2 SPZ1 SSBP3 TFIP11 TRAF2 TRIM27 TRIM37 TRIM54 TSACC TXLNA USHBP1 UTRN VCP VPS52 ZBTB9 ZRANB1
Entrez ID		283234	1838
HPRD ID		10986	09091
Ensembl ID		ENSG00000168071	ENSG00000138101
Uniprot IDs		A6NC98 B2RTU8	B7Z202 B7Z6A9 E7EVB6 E9PEY4 O60941 Q1I0L3
PDB IDs
Enriched GO Terms of Interacting Partners?
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