CCR10 and RAB5C

Data Source:
BioGRID (proximity labelling technology)

		CCR10	RAB5C
Description		C-C motif chemokine receptor 10	RAB5C, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Neutrophil Degranulation Plasma Membrane To Endosome Transport
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		10 interacting genes: ARPC3 CCL19 CCL2 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A	15 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17
Entrez ID		2826	5878
HPRD ID		02586	04947
Ensembl ID		ENSG00000184451	ENSG00000108774
Uniprot IDs		P46092	A0A024R1U4 P51148
PDB IDs			4KYI
Enriched GO Terms of Interacting Partners?
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