GPD2 and SLC25A12

Data Source:
BioGRID (affinity chromatography technology)

		GPD2	SLC25A12
Description		glycerol-3-phosphate dehydrogenase 2	solute carrier family 25 member 12
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Glycerol-3-phosphate Dehydrogenase Complex	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Glycerol-3-phosphate Dehydrogenase (quinone) Activity Calcium Ion Binding Sn-glycerol-3-phosphate:ubiquinone-8 Oxidoreductase Activity	L-glutamate Transmembrane Transporter Activity Calcium Ion Binding L-aspartate Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding
	Biological Process	Glycerol-3-phosphate Metabolic Process Glycerophosphate Shuttle Glycerol Catabolic Process	Gluconeogenesis Glutamate Biosynthetic Process Transport Positive Regulation Of Glucose Metabolic Process Aspartate Transmembrane Transport L-glutamate Transmembrane Transport Positive Regulation Of Myelination Malate-aspartate Shuttle Response To Calcium Ion L-aspartate Transmembrane Transport Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Positive Regulation Of ATP Biosynthetic Process
Pathways		Synthesis of PA Triglyceride catabolism	Mitochondrial protein import Gluconeogenesis Aspartate and asparagine metabolism
Drugs			Aspartic acid
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Depression ( 29700475) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Motion sickness ( 25628336) Myopia ( 27182965) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Refractive error ( 32231278) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Ulcerative colitis ( 25082827) Urinary albumin-to-creatinine ratio ( 31630189)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: ALDOA	1 interacting genes: JUND
Entrez ID		2820	8604
HPRD ID		00715	04719
Ensembl ID		ENSG00000115159	ENSG00000115840
Uniprot IDs		P43304 Q53T76	O75746
PDB IDs			4P5X 4P60
Enriched GO Terms of Interacting Partners?
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