AMY2A and GP2

Data Source:
HPRD (in vitro)

		AMY2A	GP2
Description		amylase alpha 2A	glycoprotein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	Alpha-amylase Activity Calcium Ion Binding Chloride Ion Binding Alpha-amylase Activity (releasing Maltohexaose)	Extracellular Matrix Structural Constituent
	Biological Process	Carbohydrate Metabolic Process Carbohydrate Catabolic Process Polysaccharide Digestion	Neutrophil Migration
Pathways		Digestion of dietary carbohydrate	Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Acarbose Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside Beta-D-Glucose 4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose Pidolic acid 5-Hydroxymethyl-Chonduritol 4,6-dideoxy-4-amino-alpha-D-glucose 6)-Alpha-L-Threo-Hexopyranose alpha-D-quinovopyranose Acarbose Derived Hexasaccharide 4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose 4)HEXOPYRANOSE
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 22344219 24861553 28892062) Body size at age 10 ( 32376654) Chronic kidney disease ( 20383146) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Type 2 diabetes ( 32499647 30718926)
Interacting Genes		3 interacting genes: GP2 IGF1R TRIAP1	6 interacting genes: AMY2A ANXA4 GLP1R JAGN1 SOX30 TSSK3
Entrez ID		279	2813
HPRD ID		00094	04279
Ensembl ID		ENSG00000243480	ENSG00000169347
Uniprot IDs		P04746 Q53F26	B7Z1G2 P55259 Q68D34
PDB IDs		1B2Y 1BSI 1CPU 1HNY 1KB3 1KBB 1KBK 1KGU 1KGW 1KGX 1U2Y 1U30 1U33 1XCW 1XCX 1XD0 1XD1 1XGZ 1XH0 1XH1 1XH2 2CPU 2QMK 2QV4 3BAI 3BAJ 3BAK 3BAW 3BAX 3BAY 3CPU 3IJ7 3IJ8 3IJ9 3OLD 3OLE 3OLG 3OLI 4GQQ 4GQR 4W93 4X9Y 5E0F 5EMY 5KEZ 5TD4 5U3A 5VA9 6OBX 6OCN
Enriched GO Terms of Interacting Partners?
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