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GNG5 and AMOTL2
Data Source:
BioGRID
(two hybrid)
GNG5
AMOTL2
Description
G protein subunit gamma 5
angiomotin like 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
G-protein Beta/gamma-subunit Complex
Extracellular Exosome
Cytosol
Plasma Membrane
Bicellular Tight Junction
Cytoplasmic Vesicle
Recycling Endosome
Molecular Function
GTPase Activity
Protein Binding
PDZ Domain Binding
G-protein Beta-subunit Binding
Protein Binding
Biological Process
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Angiogenesis
Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Wnt Signaling Pathway
Actin Cytoskeleton Organization
Regulation Of Cell Migration
Hippo Signaling
Pathways
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Signaling by Hippo
Drugs
Diseases
GWAS
Cadmium levels (
26025379
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Interacting Genes
12 interacting genes:
AMOTL2
EPS15L1
GNB1
GNB2
GNB3
GNB4
GNB5
GOLGA2
KRT31
KRT40
MDFI
TRAF1
91 interacting genes:
AMOT
BFSP2
BLZF1
BRMS1L
BYSL
CARD9
CCDC185
CCDC196
CCDC57
CCHCR1
CDC37
CDR2
CHCHD3
CINP
CYTH4
DAXX
DDIT3
DTNB
DYNLL1
DZIP1L
EIF4E2
FAM184A
FAM90A1
FBXO7
FCRL5
FXR2
GCC1
GNG11
GNG5
GOLGA2
GSTM5
KIF9
KRT1
KRT13
KRT15
KRT19
KRT20
KRT31
KRT38
KRTAP10-5
KRTAP4-2
L3MBTL2
LMNB2
LMO3
LMO4
MAD1L1
MAGEA4
MAGOHB
MFAP1
MORF4L2
MPP1
MTMR6
MTNR1A
MYO5B
NDC80
NF2
NFIL3
NME7
NTAQ1
PIBF1
PPP2CA
PPP2R1A
PRKAA2
PRPF18
PSMC3
RAD51D
RALBP1
RASAL3
RASSF5
RNF20
RNF40
RNF8
SAAL1
SH3RF2
SMARCE1
SOGA1
SP100
SPAG5
SPOP
SPP1
TCEA2
THRA
TMCC2
TNKS2
TRAF2
TRIM27
TSGA10IP
YES1
ZBED1
ZBTB16
ZGPAT
Entrez ID
2787
51421
HPRD ID
11865
16485
Ensembl ID
ENSG00000174021
ENSG00000114019
Uniprot IDs
P63218
Q9Y2J4
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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