AMT and SLMAP

Data Source:
BioGRID (biochemical)

		AMT	SLMAP
Description		aminomethyltransferase	sarcolemma associated protein
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix	Smooth Endoplasmic Reticulum Microtubule Organizing Center Integral Component Of Plasma Membrane Sarcolemma
	Molecular Function	Aminomethyltransferase Activity Transaminase Activity	Protein Binding
	Biological Process	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System	Muscle Contraction Protein Localization To Plasma Membrane Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity
Pathways		Glycine degradation
Drugs		Tetrahydrofolic acid NADH 5-methyltetrahydrofolic acid
Diseases		Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptom (depressed mood) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 27841878 30578418) FEV1 ( 30804560) Late-onset Alzheimer's disease ( 27770636) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Peak expiratory flow ( 30804560)
Interacting Genes		2 interacting genes: PDLIM4 VAC14	1 interacting genes: STK3
Entrez ID		275	7871
HPRD ID		01997	04079
Ensembl ID		ENSG00000145020	ENSG00000163681
Uniprot IDs		A0A024R2U7 P48728	B7Z6C7 B7Z964 Q14BN4
PDB IDs		1WSR 1WSV	6AKM 6AR0 6AR2
Enriched GO Terms of Interacting Partners?
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