GLUD1 and ORM1

Data Source:
BioGRID (two hybrid)

		GLUD1	ORM1
Description		glutamate dehydrogenase 1	orosomucoid 1
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding	Protein Binding
	Biological Process	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Tricarboxylic Acid Metabolic Process	Platelet Degranulation Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation
Pathways		Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism	Platelet degranulation Neutrophil degranulation
Drugs		Glutamic acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride	Amsacrine Lidocaine Progesterone Chlorpromazine Dipyridamole Thalidomide
Diseases
GWAS		Renal underexcretion gout ( 32238385)	End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)
Interacting Genes		11 interacting genes: ASGR2 CRP DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 ORM1 STAT5A VTN	9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63
Entrez ID		2746	5004
HPRD ID		11748	00724
Ensembl ID		ENSG00000148672	ENSG00000229314
Uniprot IDs		E9KL48 P00367	P02763
PDB IDs		1L1F 1NR1 6DQG	3KQ0
Enriched GO Terms of Interacting Partners?
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