CECR2 and PRICKLE1

Data Source:
BioGRID (affinity chromatography technology)

		CECR2	PRICKLE1
Description		CECR2 histone acetyl-lysine reader	prickle planar cell polarity protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus CERF Complex	Nucleus Cytosol Nuclear Membrane
	Molecular Function		Protein Binding Zinc Ion Binding
	Biological Process	Neural Fold Formation Neural Tube Closure Apoptotic DNA Fragmentation Cytoskeleton Organization Single Fertilization Vesicle-mediated Transport ATP-dependent Chromatin Remodeling Inner Ear Receptor Cell Stereocilium Organization Cytoskeleton-dependent Cytokinesis Cochlea Development Execution Phase Of Apoptosis	Neural Tube Closure Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Aorta Development Negative Regulation Of Transcription, DNA-templated Wnt Signaling Pathway, Planar Cell Polarity Pathway Coronary Vasculature Development Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation
Pathways			Asymmetric localization of PCP proteins
Drugs
Diseases			Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)	Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229) Blood urea nitrogen levels ( 31152163) Colorectal cancer ( 30529582 31826910) Endometrial cancer (Non-endometrioid histology) ( 30093612) Graves' disease ( 22922229) Heart failure ( 20445134) Hip circumference adjusted for BMI ( 28552196) Impulsivity (non-planning) ( 30718321) Inferior parietal cortex volume ( 31530798) Multiple sclerosis ( 31604244) Night sleep phenotypes ( 27126917) Parkinson's disease ( 27182965) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		2 interacting genes: LRPPRC UXT	7 interacting genes: BYSL JRK KIF9 PRPF31 SMURF2 UTP14C VIP
Entrez ID		27443	144165
HPRD ID		10463	16341
Ensembl ID		ENSG00000099954	ENSG00000139174
Uniprot IDs		B7WPH3 Q9BXF3	A0A024R0W7 B3KVG3 B3KVG6 Q96MT3
PDB IDs		3NXB 5V84
Enriched GO Terms of Interacting Partners?
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