POLL and MAGEA2B

Data Source:
BioGRID (two hybrid)

		POLL	MAGEA2B
Description		DNA polymerase lambda	MAGE family member A2B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus PML Body
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Replication Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Sumoylation Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation
Pathways		Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Interacting Genes		40 interacting genes: APP CCNDBP1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1	24 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 CEP57L1 COQ4 COX7C DYNLRB1 KRT8P12 MBD3 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TRIM28 TRIM31 TUBB ZNF655
Entrez ID		27343	266740
HPRD ID		09394	14347
Ensembl ID		ENSG00000166169	ENSG00000183305
Uniprot IDs		A8K860 B4DE17 Q9UGP5	A0A024RC17 P43356
PDB IDs		1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G
Enriched GO Terms of Interacting Partners?
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