SPINK4 and SIGMAR1

Data Source:
BioGRID (biochemical)

		SPINK4	SIGMAR1
Description		serine peptidase inhibitor Kazal type 4	sigma non-opioid intracellular receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Opioid Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization
Pathways			Potential therapeutics for SARS
Drugs			Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS		Influenza A (H1N1) infection ( 26379185) Mild influenza (H1N1) infection ( 26379185) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		1 interacting genes: SGTB	3 interacting genes: ANK2 ITPR3 PDZD11
Entrez ID		27290	10280
HPRD ID		11598	03580
Ensembl ID		ENSG00000122711	ENSG00000147955
Uniprot IDs		O60575 V9HWG8	A2A3U5 B4DR71 Q99720
PDB IDs			5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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