SIGMAR1 and PDZD11

Data Source:
BioGRID (two hybrid)

		SIGMAR1	PDZD11
Description		sigma non-opioid intracellular receptor 1	PDZ domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	Opioid Receptor Activity Protein Binding	Protein Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Potential therapeutics for SARS	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs		Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS
Interacting Genes		3 interacting genes: ANK2 ITPR3 PDZD11	5 interacting genes: ATP2B2 ATP7A MAGI2 PLEKHA5 SIGMAR1
Entrez ID		10280	51248
HPRD ID		03580	06622
Ensembl ID		ENSG00000147955	ENSG00000120509
Uniprot IDs		A2A3U5 B4DR71 Q99720	Q5EBL8
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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