GJB5 and VSTM1

Data Source:
BioGRID (two hybrid)

		GJB5	VSTM1
Description		gap junction protein beta 5	V-set and transmembrane domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Connexin Complex Integral Component Of Membrane	Extracellular Space Integral Component Of Membrane
	Molecular Function	Gap Junction Channel Activity Protein Binding	Cytokine Activity
	Biological Process	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development	Immune System Process Signal Transduction
Pathways		Gap junction assembly
Drugs
Diseases
GWAS		Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)	Small cell lung carcinoma ( 28604730)
Interacting Genes		44 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1	28 interacting genes: ADGRG3 APH1B AQP6 ARL13B CD53 CLDN7 CLDN9 CLEC10A COQ9 ERGIC3 FATE1 FBXO2 FCGR1A FNDC9 GJB5 GOLM1 GPX8 HCST KCNJ6 LAMP1 LMNA LRRC4C MANSC1 MFSD4B MRM1 PLPP2 STMN4 TMEM248
Entrez ID		2709	284415
HPRD ID		06840	15615
Ensembl ID		ENSG00000189280	ENSG00000189068
Uniprot IDs		A0A654IE64 O95377	D2DJS5 D2DJS6 Q6UX27
PDB IDs
Enriched GO Terms of Interacting Partners?
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