DNAJC2 and HSPA14

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vitro)

		DNAJC2	HSPA14
Description		DnaJ heat shock protein family (Hsp40) member C2	heat shock protein family A (Hsp70) member 14
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Membrane	Nucleus Cytoplasm Cytosol Ribosome Plasma Membrane Membrane
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Hsp70 Protein Binding Histone Binding Ubiquitin Modification-dependent Histone Binding	Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	DNA Replication Chromatin Organization Positive Regulation Of Transcription, DNA-templated 'de Novo' Cotranslational Protein Folding Regulation Of Cellular Response To Heat Negative Regulation Of DNA Biosynthetic Process	Vesicle-mediated Transport Cellular Response To Unfolded Protein Protein Refolding 'de Novo' Cotranslational Protein Folding Chaperone Cofactor-dependent Protein Refolding
Pathways		Regulation of HSF1-mediated heat shock response	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS			Night sleep phenotypes ( 27126917) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		2 interacting genes: H2AC18 HSPA14	6 interacting genes: BARD1 BRCA1 DNAJC2 FAM107A PAXIP1 STIP1
Entrez ID		27000	51182
HPRD ID		19072	07021
Ensembl ID		ENSG00000105821	ENSG00000187522
Uniprot IDs		Q99543	B0YIZ1 Q0VDF9 Q8TAQ0
PDB IDs		2M2E 6CGH
Enriched GO Terms of Interacting Partners?
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