GHSR and CORT

Data Source:
HPRD (in vivo)

		GHSR	CORT
Description		growth hormone secretagogue receptor	cortistatin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Neuron Projection Membrane Raft Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse Integral Component Of Synaptic Membrane	Extracellular Region Extracellular Space Fanconi Anaemia Nuclear Complex Synapse FANCM-MHF Complex
	Molecular Function	Growth Hormone Secretagogue Receptor Activity G Protein-coupled Receptor Activity Protein Binding Growth Hormone-releasing Hormone Receptor Activity Peptide Hormone Binding	G Protein-coupled Receptor Binding Chromatin Binding Neuropeptide Hormone Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Spermatogenesis Learning Or Memory Actin Polymerization Or Depolymerization Adult Feeding Behavior Response To Hormone Hormone-mediated Signaling Pathway Negative Regulation Of Norepinephrine Secretion Growth Hormone Secretion Response To Food Negative Regulation Of Appetite Positive Regulation Of Appetite Response To Follicle-stimulating Hormone Response To Estradiol Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Ghrelin Secretion Positive Regulation Of Multicellular Organism Growth Regulation Of Hindgut Contraction Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Insulin Secretion Decidualization Negative Regulation Of Inflammatory Response Regulation Of Synapse Assembly Regulation Of Transmission Of Nerve Impulse Regulation Of Growth Hormone Secretion Response To Growth Hormone Cellular Response To Lipopolysaccharide Response To Dexamethasone Negative Regulation Of Locomotion Involved In Locomotory Behavior Cellular Response To Thyroid Hormone Stimulus Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Postsynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Postsynapse Organization Positive Regulation Of Small Intestinal Transit Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Eating Behavior Response To Monosodium Glutamate Positive Regulation Of Small Intestine Smooth Muscle Contraction Regulation Of Gastric Motility Positive Regulation Of Vascular Endothelial Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Negative Regulation Of Macrophage Apoptotic Process	Resolution Of Meiotic Recombination Intermediates G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Replication Fork Processing
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Ulimorelin Macimorelin Echinacoside
Diseases
GWAS		Chronotype ( 30696823) Cocaine dependence ( 31212010) Height ( 20881960 25282103 25429064 23563607 31562340) Metabolite levels ( 23823483)	Male-pattern baldness ( 28196072)
Interacting Genes		3 interacting genes: CORT DRD1 GHRL	7 interacting genes: GHSR MRGPRX2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		2693	1325
HPRD ID		03541	04150
Ensembl ID		ENSG00000121853	ENSG00000241563
Uniprot IDs		Q92847	O00230 Q8IUV6
PDB IDs		6KO5
Enriched GO Terms of Interacting Partners?
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