GFI1 and CSDE1

Data Source:
BioGRID (affinity chromatography technology)

		GFI1	CSDE1
Description		growth factor independent 1 transcriptional repressor	cold shock domain containing E1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix Nuclear Body Transcription Repressor Complex	P-body Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Stress Granule CRD-mediated MRNA Stability Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding RNA Stem-loop Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Calcidiol 1-monooxygenase Activity Negative Regulation Of Vitamin D Biosynthetic Process Negative Regulation Of Neuron Projection Development Viral Process Hemopoiesis Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Regulation Of Histone H3-K4 Methylation Positive Regulation Of Interleukin-6-mediated Signaling Pathway Cellular Response To Lipopolysaccharide	Regulation Of Translational Initiation Male Gonad Development Stress Granule Assembly Nuclear-transcribed MRNA Catabolic Process, No-go Decay IRES-dependent Viral Translational Initiation
Pathways		Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Multiple sclerosis ( 31604244) Multiple sclerosis and type 2 diabetes (pleiotropy) ( 26920376) Systemic lupus erythematosus ( 28714469)	Autism ( 24189344)
Interacting Genes		6 interacting genes: FBXW7 GSK3B PIAS3 PICK1 RUNX1T1 SPI1	10 interacting genes: C11orf68 ERBB2 FAM9B HID1 HNRNPD PABPC1 PCSK7 STT3A SYNCRIP WNK1
Entrez ID		2672	7812
HPRD ID		07527	15949
Ensembl ID		ENSG00000162676	ENSG00000009307
Uniprot IDs		Q99684	A0A024R0E2 A0A024R0K2 O75534
PDB IDs			1WFQ 1X65 2YTV 2YTX 2YTY
Enriched GO Terms of Interacting Partners?
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