GDI1 and PACS1

Data Source:
BioGRID (affinity chromatography technology)

		GDI1	PACS1
Description		GDP dissociation inhibitor 1	phosphofurin acidic cluster sorting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath	Golgi Apparatus Cytosol COPI-coated Vesicle
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding	Protein Binding Ion Channel Binding
	Biological Process	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane
Pathways		RAB GEFs exchange GTP for GDP on RABs	Nef mediated downregulation of MHC class I complex cell surface expression
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006)
Interacting Genes		15 interacting genes: CDC42 EPB41 GNL1 LNX1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4	10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4
Entrez ID		2664	55690
HPRD ID		02114	06320
Ensembl ID		ENSG00000203879	ENSG00000175115
Uniprot IDs		A0A0S2Z3X8 P31150	A0A024R5H6 Q6VY07
PDB IDs
Enriched GO Terms of Interacting Partners?
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