OPN1MW and RANBP2

Data Source:
HPRD (in vivo)

		OPN1MW	RANBP2
Description		opsin 1, medium wave sensitive	RAN binding protein 2
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Disc Membrane	Nuclear Envelope Annulate Lamellae Nuclear Pore Nucleoplasm Cytoplasm Mitochondrion Cytosol Membrane Nuclear Membrane Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Host Cell Nuclear Pore Cytoplasmic Filaments Nuclear Pore Nuclear Basket Cytoplasmic Periphery Of The Nuclear Pore Complex
	Molecular Function	G Protein-coupled Photoreceptor Activity Photoreceptor Activity Identical Protein Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity GTPase Activator Activity Protein Binding Cyclosporin A Binding SUMO Transferase Activity Small GTPase Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Retinoid Metabolic Process G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Detection Of Visible Light Protein-chromophore Linkage Positive Regulation Of Cytokinesis Cellular Response To Light Stimulus	Protein Peptidyl-prolyl Isomerization Response To Amphetamine Regulation Of Glycolytic Process Regulation Of Gluconeogenesis MRNA Export From Nucleus TRNA Export From Nucleus Protein Folding NLS-bearing Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Positive Regulation Of Glucokinase Activity Positive Regulation Of GTPase Activity Centrosome Localization Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		The retinoid cycle in cones (daylight vision) Retinoid cycle disease events G alpha (i) signalling events Opsins	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Colorblindness, including: Dichromacy; Anomalous trichromacy Blue cone monochromacy
GWAS			Attention deficit hyperactivity disorder ( 29325848) Beard thickness ( 26926045) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		2 interacting genes: ARR3 RANBP2	38 interacting genes: AKAP13 ARID4B CALM1 CDCA8 CUL1 FHOD1 HDAC4 IFT140 IPO5 KPNA1 KPNA2 KPNB1 LRPAP1 MAP2K7 MDM2 MYBPC2 NFX1 NUP62 NXF1 OPN1LW OPN1MW PDLIM3 PRKN PTEN RAN RANGAP1 SENP1 SP100 SUMO1 SUMO2 TAF1 TNPO1 TOP2B UBE2I UBTD1 WAS XPO1 XPOT
Entrez ID		2652	5903
HPRD ID		02365	03111
Ensembl ID		ENSG00000268221	ENSG00000153201
Uniprot IDs		P04001 P0DN77 P0DN78	P49792
PDB IDs		1KPW	1RRP 1XKE 1Z5S 2LAS 3UIN 3UIO 3UIP 4GA0 4I9Y 4L6E 4LQW 5CLL 5CLQ
Enriched GO Terms of Interacting Partners?
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