GCDH and THTPA

Data Source:
BioGRID (affinity chromatography technology)

		GCDH	THTPA
Description		glutaryl-CoA dehydrogenase	thiamine triphosphatase
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Cytosol
	Molecular Function	Fatty-acyl-CoA Binding Glutaryl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding	Magnesium Ion Binding Protein Binding Hydrolase Activity Thiamin-triphosphatase Activity
	Biological Process	Lysine Catabolic Process Tryptophan Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Fatty-acyl-CoA Biosynthetic Process	Generation Of Precursor Metabolites And Energy Thiamine Metabolic Process Dephosphorylation Thiamine Diphosphate Metabolic Process Thiamine-containing Compound Metabolic Process
Pathways		Lysine catabolism	Vitamin B1 (thiamin) metabolism
Drugs		Flavin adenine dinucleotide S-4-Nitrobutyryl-CoA
Diseases		Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency
GWAS		Blood metabolite levels ( 24816252) Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252 19862010) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		10 interacting genes: A2M APOE CDC37 ECSIT EXOC6 MAST1 NOS3 PSEN1 PSEN2 RNF32	1 interacting genes: TLX3
Entrez ID		2639	79178
HPRD ID		01977	15505
Ensembl ID		ENSG00000105607	ENSG00000259431
Uniprot IDs		A0A024R7F9 Q92947	G3V5Q5 Q9BU02
PDB IDs		1SIQ 1SIR 2R0M 2R0N	3BHD 3TVL
Enriched GO Terms of Interacting Partners?
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