GC and SERF2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GC	SERF2
Description		GC vitamin D binding protein	small EDRK-rich factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cytosol Lysosomal Lumen Extracellular Exosome Blood Microparticle	Nucleus Cytosol
	Molecular Function	Actin Binding Vitamin D Binding Vitamin Transmembrane Transporter Activity Calcidiol Binding	Molecular_function
	Biological Process	Transport Vitamin Transmembrane Transport Vitamin D Metabolic Process Vitamin Transport	Protein Destabilization
Pathways		Vitamin D (calciferol) metabolism
Drugs		Vitamin D
Diseases
GWAS		Blood protein levels ( 29875488) Granulocyte count ( 27863252) Lymphocyte counts ( 32888494) Metabolite levels ( 22916037) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Neutrophil count ( 32888494 27863252) Non-alcoholic fatty liver disease histology (other) ( 23213074) Platelet count ( 32888494) Plateletcrit ( 32888494) Refractive error ( 32231278) Serum 25-Hydroxyvitamin D levels ( 29545823 29325163 31841498) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Serum vitamin D-binding protein levels ( 24740207) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Vitamin D insufficiency ( 20541252) Vitamin D levels ( 29343764 22673963 20418485 25208829) Vitamin D levels (dietary vitamin D intake interaction) ( 29343764) White blood cell count ( 32888494 27863252)
Interacting Genes		12 interacting genes: ACTA1 ACTA2 ACTC1 C3 CCND3 CDC73 CUBN GRB2 LRIF1 LRP2 PIK3R3 SERF2	17 interacting genes: BOLL CHD3 DAB1 GC KRTAP10-3 MDFI NELFCD PSMA3 PSME3 PTPN11 QKI RBPMS RHOXF2 SP4 THAP1 UPF2 WT1
Entrez ID		2638	10169
HPRD ID		00749	05447
Ensembl ID		ENSG00000145321	ENSG00000140264
Uniprot IDs		P02774	P84101
PDB IDs		1J78 1J7E 1KW2 1KXP 1LOT 1MA9
Enriched GO Terms of Interacting Partners?
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