BLOC1S6 and BLOC1S2

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		BLOC1S6	BLOC1S2
Description		biogenesis of lysosomal organelles complex 1 subunit 6	biogenesis of lysosomal organelles complex 1 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex Presynapse Axon Cytoplasm	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Anterograde Axonal Transport Synaptic Vesicle Docking Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		49 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3	35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3
Entrez ID		26258	282991
HPRD ID		16055	12526
Ensembl ID		ENSG00000104164	ENSG00000196072
Uniprot IDs		B3KY40 H3BST1 Q9UL45	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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