CHTOP and APOBEC3C

Data Source:
BioGRID (two hybrid)

		CHTOP	APOBEC3C
Description		chromatin target of PRMT1	apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Nucleoplasm Nucleolus Nuclear Speck Cytoplasmic Ribonucleoprotein Granule	P-body Nucleus Cytoplasm
	Molecular Function	RNA Binding Protein Binding Methyl-CpG Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	In Utero Embryonic Development RNA Export From Nucleus MRNA Export From Nucleus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Histone Methylation MRNA 3'-end Processing Positive Regulation Of ATPase Activity Positive Regulation Of Helicase Activity	Cytidine Deamination Negative Regulation Of Transposition Viral Process Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS			Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		12 interacting genes: APOBEC3C APP DDX39A DDX39B ERH KHDRBS2 PHLDB3 RBM3 SMN1 SMN2 SNRPA SRPK2	17 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581
Entrez ID		26097	27350
HPRD ID		13163	09671
Ensembl ID		ENSG00000160679	ENSG00000244509
Uniprot IDs		A0A087X1B7 Q9Y3Y2	Q9NRW3
PDB IDs			3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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