OSBPL3 and STK35

Data Source:
BioGRID (two hybrid)

		OSBPL3	STK35
Description		oxysterol binding protein like 3	serine/threonine kinase 35
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body
	Molecular Function	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Bile Acid Biosynthetic Process Sterol Transport	Protein Phosphorylation Meiotic Cell Cycle
Pathways		Synthesis of bile acids and bile salts
Drugs			Fostamatinib
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)	Adult body size ( 32376654) Early spontaneous preterm birth ( 31194736) Immune response to measles-mumps-rubella vaccine ( 24811271) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		25 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835	6 interacting genes: BMPR1B OSBPL3 PDLIM1 SMAD4 SMURF1 TGFBR1
Entrez ID		26031	140901
HPRD ID		09474	11612
Ensembl ID		ENSG00000070882	ENSG00000125834
Uniprot IDs		Q9H4L5	Q8TDR2
PDB IDs		7CYZ
Enriched GO Terms of Interacting Partners?
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