PNKD and KCTD9

Data Source:
BioGRID (two hybrid)

		PNKD	KCTD9
Description		PNKD metallo-beta-lactamase domain containing	potassium channel tetramerization domain containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Membrane
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Protein Binding Metal Ion Binding	Protein Binding Identical Protein Binding Protein Self-association Cullin Family Protein Binding
	Biological Process	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization
Pathways
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)	Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		5 interacting genes: APP ENO3 KCTD9 MAGEA11 MYL12B	94 interacting genes: ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 C19orf54 C7orf31 C9orf24 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD CUL3 DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6A GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 NUP35 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PPP1R32 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 STX11 SYT6 TASOR2 TEPSIN TEX37 TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76
Entrez ID		25953	54793
HPRD ID		11369	13772
Ensembl ID		ENSG00000127838	ENSG00000104756
Uniprot IDs		A0A024R415 Q8N490	Q7L273
PDB IDs			5BXH
Enriched GO Terms of Interacting Partners?
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