FAM98A and MIR222

Data Source:
BioGRID (unspecified method)

		FAM98A	MIR222
Description		family with sequence similarity 98 member A	microRNA 222
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-splicing Ligase Complex	Extracellular Space Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Protein Methyltransferase Activity	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Lysosome Localization Positive Regulation Of Ruffle Assembly	Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Angiogenesis Negative Regulation Of Interleukin-21 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Apoptotic Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Axon Regeneration Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cell Adhesion Molecule Production Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Schwann Cell Migration Negative Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756) Hypertension (young onset) ( 19421330) IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7) ( 26741287) Irritable bowel syndrome ( 29626450) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933) Perceived intensity of aspartame ( 31005972) Response to antidepressants in depression ( 27622933) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		64 interacting genes: MIR1-2 MIR106A MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I RTRAF	75 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LRPPRC MATR3 MSI2 NONO PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PURA QARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		25940	407007
HPRD ID		16808
Ensembl ID		ENSG00000119812	ENSG00000207725
Uniprot IDs		B4DT23 I6L9E8 Q8NCA5
PDB IDs
Enriched GO Terms of Interacting Partners?
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