ZDHHC5 and MS4A6A

Data Source:
BioGRID (genetic interference)

		ZDHHC5	MS4A6A
Description		zinc finger DHHC-type palmitoyltransferase 5	membrane spanning 4-domains A6A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Dendrite Phagocytic Vesicle	Trans-Golgi Network Integral Component Of Membrane
	Molecular Function	Protein Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Protein Binding
	Biological Process	Protein Phosphopantetheinylation Protein Palmitoylation Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Phagocytic Vesicle
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Schizophrenia ( 28991256 25056061 29483656)	Alzheimer's disease ( 21460840) Alzheimer's disease (late onset) ( 30617256 24162737 28714976) Alzheimer's disease in APOE e4- carriers ( 25778476) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) C-reactive protein levels ( 30388399) Cerebrospinal fluid sTREM-2 levels ( 31708768) Factor VII activity ( 30642921) Factor VII activity or levels ( 30642921) Family history of Alzheimer's disease ( 30617256) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422 26561523) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549 28869591) Lymphocyte percentage of white cells ( 32888494) Methadone dose in opioid dependence ( 28115739) Neutrophil count ( 32888494)
Interacting Genes		1 interacting genes: SRPK2	1 interacting genes: GPRC5D
Entrez ID		25921	64231
HPRD ID		15720	09414
Ensembl ID		ENSG00000156599	ENSG00000110077
Uniprot IDs		A0A024R546 Q9C0B5	A0A024R516 A0A024R554 B4DUN6 E9PSA9 Q9H2W1
PDB IDs
Enriched GO Terms of Interacting Partners?
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