IFFO1 and ERC1

Data Source:
BioGRID (affinity chromatography technology)

		IFFO1	ERC1
Description		intermediate filament family orphan 1	ELKS/RAB6-interacting/CAST family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Intermediate Filament Nuclear Matrix Site Of Double-strand Break	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Ciliary Basal Body Presynaptic Membrane Synapse Cytoskeleton Of Presynaptic Active Zone
	Molecular Function	Protein Binding	Protein Binding PDZ Domain Binding Small GTPase Binding Leucine Zipper Domain Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Protein Localization To Site Of Double-strand Break DNA Double-strand Break Attachment To Nuclear Envelope	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Neuromuscular Synaptic Transmission Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Regulation Of Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 28552196)	Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867)
Interacting Genes		8 interacting genes: ACAP1 GFI1B LMNA NDN RHOU RNF183 TCHP XRCC4	9 interacting genes: APP DNAJC5 ITSN2 PPFIA1 RAB6A RAB6B RIMS1 SRPK2 YWHAG
Entrez ID		25900	23085
HPRD ID		09988	06181
Ensembl ID		ENSG00000010295	ENSG00000082805
Uniprot IDs		A0A087WZ16 B4DQQ1 Q0D2I5 Q6P593 Q9Y4M3	G8JLD3 Q8IUD2 X6RLX0
PDB IDs		6ABO
Enriched GO Terms of Interacting Partners?
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