SPEF1 and KIZ

Data Source:
BioGRID (genetic interference)

		SPEF1	KIZ
Description		sperm flagellar 1	kizuna centrosomal protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Microvillus Axoneme Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Filopodium Ciliary Tip 9+2 Motile Cilium Axonemal Central Apparatus	Cytoplasm Centrosome Cell Projection
	Molecular Function	Molecular_function Actin Binding Protein Binding Microtubule Binding	Protein Binding Protein Kinase Binding
	Biological Process	Microtubule Bundle Formation Cilium Movement Negative Regulation Of Microtubule Depolymerization Cell Migration Lamellipodium Assembly Filopodium Assembly Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axonemal Central Apparatus Assembly Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway	Spindle Organization
Pathways
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal volume ( 29860282) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Height ( 31562340)
Interacting Genes		5 interacting genes: CYSRT1 KRT40 KRTAP13-2 PLEKHF2 ZBED1	3 interacting genes: MEOX2 TACC3 TFIP11
Entrez ID		25876	55857
HPRD ID		09839	12760
Ensembl ID		ENSG00000101222	ENSG00000088970
Uniprot IDs		Q9Y4P9	A0A087X251 Q2M2Z5
PDB IDs		2EE7
Enriched GO Terms of Interacting Partners?
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