RPL36 and PIP5K1C

Data Source:
BioGRID (fluorescent resonance energy transfer)

		RPL36	PIP5K1C
Description		ribosomal protein L36	phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
Image
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome	Phagocytic Cup Uropod Nucleoplasm Cytosol Adherens Junction Focal Adhesion Endosome Membrane Ruffle Membrane Presynapse
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Phosphatidylinositol Biosynthetic Process Phagocytosis Regulation Of Phosphatidylinositol 3-kinase Signaling Synaptic Vesicle Exocytosis Actin Cytoskeleton Organization Neutrophil Chemotaxis Adherens Junction Assembly Phosphatidylinositol Phosphorylation Synaptic Vesicle Endocytosis Membrane Organization Clathrin-dependent Endocytosis Cell-cell Adhesion
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Synthesis of PIPs at the plasma membrane SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Clathrin-mediated endocytosis
Drugs
Diseases			Lethal congenital contractural syndrome (LCCS)
GWAS
Interacting Genes		4 interacting genes: APP DUX4 PTEN RPL18A	17 interacting genes: AKT1 AKT2 AP1B1 AP2B1 ARF6 BTK CDH1 CDK5 HDHD2 ITGB1 LAPTM4B LRP2 NEDD4 PKD1 SMURF1 SRC TLN2
Entrez ID		25873	23396
HPRD ID		10201	05834
Ensembl ID		ENSG00000130255	ENSG00000186111
Uniprot IDs		Q9Y3U8	O60331
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	2G35 3H1Z 3H85
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?