COG4 and PLA2G15

Data Source:
BioGRID (affinity chromatography technology)

		COG4	PLA2G15
Description		component of oligomeric golgi complex 4	phospholipase A2 group XV
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GO Annotations	Cellular Component	Golgi Membrane Cytosol Golgi Transport Complex Trans-Golgi Network Membrane	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Lysophospholipase Activity Triglyceride Lipase Activity Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phosphatidyl Phospholipase B Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Golgi Vesicle Prefusion Complex Stabilization	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Hydrolysis of LPC
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)	Body size at age 10 ( 32376654) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		15 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 FAM110A FARSA MTNR1B PSMA1 SEPTIN2 SORBS3 TXNDC9	2 interacting genes: IMMT RNF7
Entrez ID		25839	23659
HPRD ID		08444	07128
Ensembl ID		ENSG00000103051	ENSG00000103066
Uniprot IDs		A0A0A0MS45 J3KNI1 Q8N8L9 Q9H9E3	Q8NCC3
PDB IDs		3HR0	4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW
Enriched GO Terms of Interacting Partners?
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