SVIP and UBXN6

Data Source:
BioGRID (two hybrid)

		SVIP	UBXN6
Description		small VCP interacting protein	UBX domain protein 6
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Plasma Membrane Secretory Granule Membrane Smooth Endoplasmic Reticulum Membrane Anchored Component Of Membrane Extracellular Exosome Tertiary Granule Membrane	Nucleus Cytoplasm Lysosomal Membrane Endosome Microtubule Organizing Center Cytosol Extrinsic Component Of Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Protein Binding Protein Self-association ATPase Binding	Protein Binding
	Biological Process	Positive Regulation Of Autophagy Negative Regulation Of Protein-containing Complex Assembly Neutrophil Degranulation Positive Regulation Of Protein Lipidation Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of VCP-NPL4-UFD1 AAA ATPase Complex Assembly	Macroautophagy Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway ERAD Pathway
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Dialysis-related mortality ( 21546767)	Delta-5 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731) Multiple sclerosis ( 31604244) Red blood cell count ( 32888494)
Interacting Genes		2 interacting genes: UBXN6 VCP	20 interacting genes: APP DAZAP2 DERL1 FAM168A GSK3B MAGEA4 MCL1 NLGN3 PLEKHB2 SMURF1 SUSD6 SVIP TRIM39 UBC UBXN10 UBXN2A UBXN2B UFD1 VCP YOD1
Entrez ID		258010	80700
HPRD ID			18253
Ensembl ID		ENSG00000198168	ENSG00000167671
Uniprot IDs		Q8NHG7	Q9BZV1
PDB IDs			6SAP
Enriched GO Terms of Interacting Partners?
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