SUN2 and APOBEC3C

Data Source:
BioGRID (two hybrid)

		SUN2	APOBEC3C
Description		Sad1 and UNC84 domain containing 2	apolipoprotein B mRNA editing enzyme catalytic subunit 3C
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	P-body Nucleus Cytoplasm
	Molecular Function	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane	Cytidine Deamination Negative Regulation Of Transposition Viral Process Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways		Meiotic synapsis	mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		4 interacting genes: HGS NRM RAB5B RPS20	17 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581
Entrez ID		25777	27350
HPRD ID		15611	09671
Ensembl ID		ENSG00000100242	ENSG00000244509
Uniprot IDs		A0A024R1P7 B4E2A6 Q9UH99	Q9NRW3
PDB IDs		3UNP 4DXR 4DXS 4DXT 4FI9	3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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