SUN2 and MAFF

Data Source:
HPRD (in vitro, in vivo)

		SUN2	MAFF
Description		Sad1 and UNC84 domain containing 2	MAF bZIP transcription factor F
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Chromatin Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Parturition Blood Coagulation Skeletal Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Meiotic synapsis	Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31562340) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) Red blood cell count ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531)
Interacting Genes		4 interacting genes: HGS NRM RAB5B RPS20	21 interacting genes: ATF3 BACH2 BATF2 BATF3 DDIT3 FOS GTF2A1L HDAC5 HOXD12 MAFG MAFIP NFE2 NFE2L1 NFE2L2 NFIL3 NR3C1 NRF1 OVOL1 PPARG PRRX1 PSAP
Entrez ID		25777	23764
HPRD ID		15611	05343
Ensembl ID		ENSG00000100242	ENSG00000185022
Uniprot IDs		A0A024R1P7 B4E2A6 Q9UH99	Q9ULX9
PDB IDs		3UNP 4DXR 4DXS 4DXT 4FI9
Enriched GO Terms of Interacting Partners?
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