SUN2 and RASD2

Data Source:
BioGRID (affinity chromatography technology)

		SUN2	RASD2
Description		Sad1 and UNC84 domain containing 2	RASD family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Plasma Membrane
	Molecular Function	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity	GTPase Activity GTP Binding Ubiquitin Conjugating Enzyme Binding G-protein Beta-subunit Binding Phosphatidylinositol 3-kinase Binding
	Biological Process	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane	Signal Transduction Locomotory Behavior Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Sumoylation Regulation Of CAMP-mediated Signaling Positive Regulation Of Protein Kinase B Signaling
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS		Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Chronotype ( 30696823) Hippocampal volume in mild cognitive impairment ( 29274321) Intelligence (MTAG) ( 29326435) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: HGS NRM RAB5B RPS20	16 interacting genes: ACVR1 BMPR1B GNB1 GNB2 GNB3 PIK3CA PIK3R1 RABAC1 RAF1 SMAD1 SMAD2 SMAD3 SMAD4 SMURF1 SMURF2 TGFBR1
Entrez ID		25777	23551
HPRD ID		15611	15210
Ensembl ID		ENSG00000100242	ENSG00000100302
Uniprot IDs		A0A024R1P7 B4E2A6 Q9UH99	Q96D21
PDB IDs		3UNP 4DXR 4DXS 4DXT 4FI9
Enriched GO Terms of Interacting Partners?
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