HYPK and PHC3

Data Source:
BioGRID (two hybrid)

		HYPK	PHC3
Description		huntingtin interacting protein K	polyhomeotic homolog 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Protein-containing Complex	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Protein N-terminus Binding	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Binding
	Biological Process	Negative Regulation Of Apoptotic Process Protein Stabilization	Multicellular Organism Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823)
Interacting Genes		28 interacting genes: BOLL C2orf68 CSNK2B CYSRT1 HNRNPF HTT KRTAP12-2 KRTAP19-5 KRTAP3-2 KRTAP3-3 KRTAP8-1 MAGEA1 MDFI NAA15 PCBP1 PHC3 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RHOXF2 SP4 TENT5A THAP1 TXLNA VENTX	4 interacting genes: AGR2 H3-4 HYPK OGT
Entrez ID		25764	80012
HPRD ID		13724	10149
Ensembl ID		ENSG00000242028	ENSG00000173889
Uniprot IDs		A0A024R5Q1 Q9NX55	B4E2T1 E7EX82 Q8NDX5
PDB IDs		6C95 6PW9	4PZN 4PZO
Enriched GO Terms of Interacting Partners?
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