RNF214 and LPXN

Data Source:
BioGRID (two hybrid)

		RNF214	LPXN
Description		ring finger protein 214	leupaxin
Image		No pdb structure
GO Annotations	Cellular Component		Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Metal Ion Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination	Regulation Of Transcription, DNA-templated Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) HDL cholesterol levels ( 32203549) Sensorimotor dexterity ( 31596458)	Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: GGA3 GOLGA2 LPXN TRIP6 ZNF76	33 interacting genes: AGXT AQP1 GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 LMO3 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RNF214 RUNX1T1 SFI1 TGFB1 TNS2 TXLNB VCL ZNF175 ZNF426
Entrez ID		257160	9404
HPRD ID		16815	05651
Ensembl ID		ENSG00000167257	ENSG00000110031
Uniprot IDs		A0A024R3D4 Q8ND24	B7Z5P7 O60711
PDB IDs			1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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