TCP11L2 and TUBA8

Data Source:
BioGRID (two hybrid)

		TCP11L2	TUBA8
Description		t-complex 11 like 2	tubulin alpha 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Signal Transduction	Microtubule Cytoskeleton Organization Mitotic Cell Cycle
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Cilium Assembly RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs			Epothilone D Patupilone
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Tourette syndrome ( 22889924)	Atrial fibrillation ( 30061737 29892015) Cerebrospinal T-tau levels ( 28247064)
Interacting Genes		5 interacting genes: APP CXXC1 HGS TUBA4A TUBA8	7 interacting genes: GRM7 LINC01554 MYC PXN SIAH1 TCP1 TCP11L2
Entrez ID		255394	51807
HPRD ID		17555	05763
Ensembl ID		ENSG00000166046	ENSG00000183785
Uniprot IDs		A0A024RBH4 Q8N4U5	Q9NY65
PDB IDs
Enriched GO Terms of Interacting Partners?
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