MBLAC1 and RHOH

Data Source:
BioGRID (two hybrid)

		MBLAC1	RHOH
Description		metallo-beta-lactamase domain containing 1	ras homolog family member H
Image			No pdb structure
GO Annotations	Cellular Component		Immunological Synapse Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Hydrolase Activity Metal Ion Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding
	Biological Process		Regulation Of Transcription, DNA-templated Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Motor Neuron Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly T Cell Differentiation Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Engulfment Of Apoptotic Cell Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Neutrophil Migration
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Microalbuminuria in type 1 diabetes ( 31537649) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		11 interacting genes: AGR2 C10orf55 FNDC8 INCA1 MYOZ2 NDUFAB1 POGZ RHOH TRAF2 TRIP13 VAC14	23 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 UTP14A XPNPEP1
Entrez ID		255374	399
HPRD ID		18584	03616
Ensembl ID		ENSG00000214309	ENSG00000168421
Uniprot IDs		A4D2B0	Q15669 Q6ICP4
PDB IDs		4V0H
Enriched GO Terms of Interacting Partners?
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