CBARP and PORCN

Data Source:
BioGRID (two hybrid)

		CBARP	PORCN
Description		CACN subunit beta associated regulatory protein	porcupine O-acyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Secretory Granule Growth Cone Synaptic Vesicle Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane AMPA Glutamate Receptor Complex Glutamatergic Synapse
	Molecular Function	Ion Channel Binding	Transferase Activity, Transferring Acyl Groups Wnt-protein Binding Palmitoleoyltransferase Activity
	Biological Process	Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Calcium Ion Transmembrane Transport	Protein Lipidation Glycoprotein Metabolic Process Wnt Signaling Pathway Protein Palmitoylation Lipid Modification Protein Palmitoleylation Canonical Wnt Signaling Pathway Wnt Protein Secretion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Pathways			WNT ligand biogenesis and trafficking LGK974 inhibits PORCN
Drugs
Diseases			Focal dermal hypoplasia; Goltz-Gorlin syndrome
GWAS
Interacting Genes		10 interacting genes: ABHD16A ATP13A1 CALHM6 MFSD5 MS4A13 NCK2 PORCN SLC35F6 SLC39A9 TRAF3IP3	9 interacting genes: APOC2 APOC4 CBARP WNT1 WNT3A WNT4 WNT5B WNT6 WNT7B
Entrez ID		255057	64840
HPRD ID		16627	06680
Ensembl ID		ENSG00000099625	ENSG00000102312
Uniprot IDs		Q8N350	Q9H237
PDB IDs
Enriched GO Terms of Interacting Partners?
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