LCORL and MIR206

Data Source:
BioGRID (unspecified method)

		LCORL	MIR206
Description		ligand dependent nuclear receptor corepressor like	microRNA 206
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	RISC Complex
	Molecular Function	DNA Binding Protein Binding Histone Methyltransferase Binding	MRNA 3'-UTR Binding Protein Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Cell Fate Commitment Negative Regulation Of Gene Expression Positive Regulation Of Myotube Differentiation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Tumor Necrosis Factor Production Gene Silencing By MiRNA Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Amyloid-beta Formation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Alzheimer's disease progression score ( 29860282) Birth length ( 25281659) Birth weight ( 23202124 31043758 27680694) BMI at 1 year old ( 31575865) BMI at 1.5 years old ( 31575865) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronotype ( 30696823) Colorectal cancer (diet interaction) ( 24743840) Diverticular disease ( 30177863) Familial squamous cell lung carcinoma ( 29924316) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Height ( 21998595 28552196 20881960 22021425 25282103 25429064 19343178 23563607 31562340 28270201 18391951 18391952 20189936) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 25673412) Infant length ( 25281659) Offspring birth weight ( 31043758) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 25673412) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		4 interacting genes: CTBP1 CTBP2 MAGEA6 MIR206	78 interacting genes: ADARB1 AIMP1 AQR C1QBP CELF1 CPSF1 CSTF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LCORL LIN28A LIN28B LRPPRC MARS1 MATR3 NOL4L NONO NUDT21 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346
Entrez ID		254251	406989
HPRD ID		10088
Ensembl ID		ENSG00000178177	ENSG00000207604
Uniprot IDs		A0A1B0GVP4 B4DSW0 Q8N3X6
PDB IDs
Enriched GO Terms of Interacting Partners?
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