MMS22L and NDUFAF4

Data Source:
BioGRID (proximity labelling technology)

		MMS22L	NDUFAF4
Description		MMS22 like, DNA repair protein	NADH:ubiquinone oxidoreductase complex assembly factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol FACT Complex MCM Complex Nuclear Replication Fork	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Calmodulin Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Replication Fork Processing	Mitochondrial Respiratory Chain Complex I Assembly
Pathways			Complex I biogenesis
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Adult body size ( 32376654) Automobile speeding propensity ( 30643258) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Chronotype ( 30696823) Gut microbiota (bacterial taxa) ( 27694959) Hand grip strength ( 29691431) Morning person ( 30696823) Multiple sclerosis (OCB status) ( 23785401) Number of sexual partners ( 30643258) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		4 interacting genes: ESCO2 FBXW7 RAD51 RPA1	1 interacting genes: NDUFAF3
Entrez ID		253714	29078
HPRD ID		12865	10795
Ensembl ID		ENSG00000146263	ENSG00000123545
Uniprot IDs		Q6ZRQ5	Q9P032
PDB IDs
Enriched GO Terms of Interacting Partners?
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