FUT8 and ZBTB10

Data Source:
BioGRID (two hybrid)

		FUT8	ZBTB10
Description		fucosyltransferase 8	zinc finger and BTB domain containing 10
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Golgi Cisterna Membrane Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Glycoprotein 6-alpha-L-fucosyltransferase Activity SH3 Domain Binding Alpha-(1->6)-fucosyltransferase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	In Utero Embryonic Development Protein N-linked Glycosylation N-glycan Processing Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Respiratory Gaseous Exchange By Respiratory System Oligosaccharide Biosynthetic Process Regulation Of Gene Expression Cell Migration Protein N-linked Glycosylation Via Asparagine Protein Glycosylation In Golgi N-glycan Fucosylation L-fucose Catabolic Process Receptor Metabolic Process GDP-L-fucose Metabolic Process Regulation Of Cellular Response To Oxidative Stress	Regulation Of Transcription By RNA Polymerase II
Pathways		Maturation of spike protein Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Hematocrit ( 32888494) Hemoglobin ( 32888494) High density lipoprotein cholesterol levels ( 29083408) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG monosialylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392 32128391) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Ischemic stroke ( 26732560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Multiple sclerosis--Brain Glutamate Levels ( 20802204) N-glycan levels ( 21908519 21203500 31163085) Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio ( 26634245) Red blood cell count ( 32888494) Systemising ( 31508503) Verbal-numerical reasoning ( 27046643)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 31959851 30929738 27182965 32296059 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887) Body mass index ( 28892062 30271922 25673413) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		2 interacting genes: FBXO7 ZBTB10	20 interacting genes: CDC7 CEP19 DCX DDX6 EHHADH FUT8 HRAS LSM4 MAGOHB MOB3C MORF4L1 MORF4L2 MYO15B PACRGL PHF1 RBM41 RNF8 USP20 UTP25 ZNF417
Entrez ID		2530	65986
HPRD ID		03994	15689
Ensembl ID		ENSG00000033170	ENSG00000205189
Uniprot IDs		A8K8P8 Q546E0 Q9BYC5	Q96DT7 Q9H9H3
PDB IDs		2DE0 6VLD 6VLE 6X5H 6X5R 6X5S 6X5T 6X5U
Enriched GO Terms of Interacting Partners?
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